diff --git a/pyqtgraph/graphicsItems/ROI.py b/pyqtgraph/graphicsItems/ROI.py
index ce6326ac..c2cb49ed 100644
--- a/pyqtgraph/graphicsItems/ROI.py
+++ b/pyqtgraph/graphicsItems/ROI.py
@@ -800,7 +800,7 @@ class ROI(GraphicsObject):
         if ev.button() == QtCore.Qt.RightButton and self.contextMenuEnabled():
             self.raiseContextMenu(ev)
             ev.accept()
-        elif ev.button() & self.acceptedMouseButtons():
+        elif ev.button() in self.acceptedMouseButtons():
             ev.accept()
             self.sigClicked.emit(self, ev)
         else:
diff --git a/pyqtgraph/graphicsItems/ViewBox/ViewBox.py b/pyqtgraph/graphicsItems/ViewBox/ViewBox.py
index 83d095b7..6725d78b 100644
--- a/pyqtgraph/graphicsItems/ViewBox/ViewBox.py
+++ b/pyqtgraph/graphicsItems/ViewBox/ViewBox.py
@@ -1243,7 +1243,7 @@ class ViewBox(GraphicsWidget):
             mask[1-axis] = 0.0
 
         ## Scale or translate based on mouse button
-        if ev.button() & (QtCore.Qt.LeftButton | QtCore.Qt.MiddleButton):
+        if ev.button() in [QtCore.Qt.LeftButton, QtCore.Qt.MiddleButton]:
             if self.state['mouseMode'] == ViewBox.RectMode and axis is None:
                 if ev.isFinish():  ## This is the final move in the drag; change the view scale now
                     #print "finish"