diff --git a/README.md b/README.md
index a071a81f..41e8407c 100644
--- a/README.md
+++ b/README.md
@@ -9,7 +9,7 @@ PyQtGraph
 [![Total alerts](https://img.shields.io/lgtm/alerts/g/pyqtgraph/pyqtgraph.svg?logo=lgtm&logoWidth=18)](https://lgtm.com/projects/g/pyqtgraph/pyqtgraph/alerts/)
 [![Language grade: Python](https://img.shields.io/lgtm/grade/python/g/pyqtgraph/pyqtgraph.svg?logo=lgtm&logoWidth=18)](https://lgtm.com/projects/g/pyqtgraph/pyqtgraph/context:python)
 
-A pure-Python graphics library for PyQt5/PySide2
+A pure-Python graphics library for PyQt5/PySide2/PySide6
 
 Copyright 2020 Luke Campagnola, University of North Carolina at Chapel Hill
 
@@ -29,33 +29,34 @@ This project supports:
 
 * All minor versions of Python released 42 months prior to the project, and at minimum the two latest minor versions.
 * All minor versions of numpy released in the 24 months prior to the project, and at minimum the last three minor versions.
-* All minor versions of Qt 5 currently supported by upstream Qt (Note, Qt 6 support is not yet implemented)
+* All minor versions of Qt 5 and Qt 6 currently supported by upstream Qt
 
 Currently this means:
 
 * Python 3.7+
-* Qt 5.12-5.15
+* Qt 5.12-6.0
 * Required
-  * PyQt5 or PySide2
+  * PyQt5, PySide2 or PySide6
   * `numpy` 1.17+
 * Optional
   * `scipy` for image processing
   * `pyopengl` for 3D graphics
     * `pyopengl` on macOS Big Sur only works with python 3.9.1+
   * `hdf5` for large hdf5 binary format support
-  * `colorcet` for supplimental colormaps
+  * `colorcet` for supplemental colormaps
 
 Qt Bindings Test Matrix
 -----------------------
 
-The following table represents the python environments we test in our CI system.  Our CI system uses Ubuntu 18.04, Windows Server 2019, and macOS 10.15 base images.
+The following table represents the python environments we test in our CI system.  Our CI system uses Ubuntu 20.04, Windows Server 2019, and macOS 10.15 base images.
 
 | Qt-Bindings    | Python 3.7         | Python 3.8         | Python 3.9         |
 | :------------- | :----------------: | :----------------: | :----------------: |
 | PySide2-5.12   | :white_check_mark: | :x:                | :x:                |
 | PyQt5-5.12     | :white_check_mark: | :x:                | :x:                |
-| PySide2-5.15   | :x:                | :white_check_mark: | :white_check_mark: |
+| PySide2-5.15   | :x:                | :white_check_mark: | :x:                |
 | PyQt5-5.15     | :x:                | :white_check_mark: | :white_check_mark: |
+| PySide6-6.0    | :x:                | :x:                | :white_check_mark: |
 
 Support
 -------