diff --git a/pyqtgraph/tests/test_reload.py b/pyqtgraph/tests/test_reload.py
index 11b12cf2..e806100f 100644
--- a/pyqtgraph/tests/test_reload.py
+++ b/pyqtgraph/tests/test_reload.py
@@ -43,8 +43,8 @@ def remove_cache(mod):
         shutil.rmtree(cachedir)
 
 @pytest.mark.skipif(
-    pg.Qt.QT_LIB == "PySide2"
-    and pg.Qt.PySide2.__version__.startswith("5.15")
+    ((pg.Qt.QT_LIB == "PySide2" and pg.Qt.PySide2.__version__.startswith("5.15"))
+     or (pg.Qt.QT_LIB == "PySide6"))
     and sys.version_info > (3, 9),
     reason="Unknown Issue")
 def test_reload():