diff --git a/pyqtgraph/imageview/ImageView.py b/pyqtgraph/imageview/ImageView.py
index e9058bdb..546d4164 100644
--- a/pyqtgraph/imageview/ImageView.py
+++ b/pyqtgraph/imageview/ImageView.py
@@ -584,7 +584,7 @@ class ImageView(QtGui.QWidget):
         # Extract image data from ROI
         axes = (self.axes['x'], self.axes['y'])
 
-        data, coords = self.roi.getArrayRegion(image.view(np.ndarray), self.imageItem, axes, returnMappedCoords=True)
+        data, coords = self.roi.getArrayRegion(image.view(np.ndarray), self.imageItem, returnMappedCoords=True)
         if data is None:
             return
 
@@ -592,7 +592,10 @@ class ImageView(QtGui.QWidget):
         if self.axes['t'] is None:
             # Average across y-axis of ROI
             data = data.mean(axis=axes[1])
-            coords = coords[:,:,0] - coords[:,0:1,0]
+            if axes == (1,0): ## we're in row-major order mode -- there's probably a better way to do this slicing dynamically, but I've not figured it out yet.
+                coords = coords[:,0,:] - coords[:,0,0:1]
+            else: #default to old way
+                coords = coords[:,:,0] - coords[:,0:1,0] 
             xvals = (coords**2).sum(axis=0) ** 0.5
         else:
             # Average data within entire ROI for each frame