diff --git a/autogen.sh b/autogen.sh
index 8afd4bfd78..a12f744542 100755
--- a/autogen.sh
+++ b/autogen.sh
@@ -32,17 +32,17 @@ autoversion=`$AUTOCONF --version 2>/dev/null | head -n 1`
 test "$autoversion" != "" && {
     echo "Using $autoversion"
 } || {
-    echo "LyX requires autoconf >= 2.59c"
+    echo "LyX requires autoconf >= 2.60"
     exit 1
 }
 
 
 case $autoversion in
-    *' '2.59d|*' '2.60[ab]|*' '2.6[0-9])
+    *' '2.60[ab]|*' '2.6[0-9])
 	;;
     *)
 	echo "This autoconf version is not supported by LyX."
-	echo "LyX only supports autoconf 2.59d-2.69."
+	echo "LyX only supports autoconf 2.60-2.69."
 	exit 1
 	;;
 esac
diff --git a/config/lyxinclude.m4 b/config/lyxinclude.m4
index 2e529ea221..a21ce0a6fc 100644
--- a/config/lyxinclude.m4
+++ b/config/lyxinclude.m4
@@ -547,9 +547,6 @@ AM_CONDITIONAL(INSTALL_MACOSX, $lyx_install_macosx)
 AM_CONDITIONAL(INSTALL_WINDOWS, $lyx_install_windows)
 AM_CONDITIONAL(INSTALL_CYGWIN, $lyx_install_cygwin)
 AM_CONDITIONAL(INSTALL_POSIX, $lyx_install_posix)
-dnl Next two lines are only for autoconf <= 2.59
-datadir='${datarootdir}'
-AC_SUBST(datarootdir)
 AC_SUBST(pkgdatadir)
 AC_SUBST(program_suffix)
 ])
diff --git a/config/qt4.m4 b/config/qt4.m4
index 3114341051..2fd66b4503 100644
--- a/config/qt4.m4
+++ b/config/qt4.m4
@@ -140,6 +140,12 @@ AC_DEFUN([QT4_DO_IT_ALL],
 	if test "$pkg_failed" != "no" ; then
 		QT4_DO_MANUAL_CONFIG
 	fi
+
+	dnl Check qt version
+	AS_VERSION_COMPARE($QT4_VERSION, $1, 
+	[LYX_ERROR([LyX requires version $1 of Qt. Only version $QT4_VERSION has been found.])
+	])
+
 	AC_PATH_PROGS(MOC4, [moc-qt4 moc],[],$qt4_cv_bin:$PATH)
 	AC_PATH_PROGS(UIC4, [uic-qt4 uic],[],$qt4_cv_bin:$PATH)
 	AC_PATH_PROGS(RCC4, [rcc-qt4 rcc],[],$qt4_cv_bin:$PATH)
diff --git a/configure.ac b/configure.ac
index ae3ba025ad..0c4d833c76 100644
--- a/configure.ac
+++ b/configure.ac
@@ -3,7 +3,7 @@ dnl Process with autoconf to generate configure script   -*- sh -*-
 AC_INIT(LyX,2.1.0dev,[lyx-devel@lists.lyx.org],[lyx])
 # Use ISO format only. The frontend needs to parse this
 AC_SUBST(LYX_DATE, ["2011-04-29"])
-AC_PREREQ(2.52)
+AC_PREREQ(2.60)
 AC_CONFIG_SRCDIR(src/main.cpp)
 AC_CONFIG_HEADERS([config.h])
 
@@ -133,7 +133,7 @@ dnl problems with the AC_REQUIRE contained in QT4_DO_IT_ALL.
 for frontend in $FRONTENDS ; do
   case "$frontend" in
     qt4)
-	  QT4_DO_IT_ALL
+	  QT4_DO_IT_ALL([4.5.0])
 	  FRONTENDS_PROGS="$FRONTENDS_PROGS lyx-qt4\$(EXEEXT)"
 	  FRONTENDS_SUBDIRS="$FRONTENDS_SUBDIRS qt4"
 	  RPM_FRONTEND="qt4"